Ducks to MLB
The following list includes every player that reached the Major League Baseball level after playing with the Long Island Ducks:
| PLAYER | YEAR(S) WITH DUCKS | TEAM PROMOTED BY | PROMOTION YEAR |
| Carlos Baerga | 2001 | Boston Red Sox | 2002 |
| Pedro Borbon Jr. | 2003 | St. Louis Cardinals | 2003 |
| Bill Pulsipher | 2004 | St. Louis Cardinals | 2005 |
| Ken Ray | 2002 | Atlanta Braves | 2006 |
| Nelson Figueroa | 2006 | New York Mets | 2008 |
| Mel Stocker | 2006 | Milwaukee Brewers | 2007 |
| Jay Gibbons | 2008 | Los Angeles Dodgers | 2010 |
| Erick Almonte | 2006 | Milwaukee Brewers | 2011 |
| Robinson Cancel | 2010 | Houston Astros | 2011 |
| Joey Gathright | 2010 | Boston Red Sox | 2011 |
| Justin Hampson | 2010 | New York Mets | 2012 |
| Kip Wells | 2010 | San Diego Padres | 2012 |
| Lew Ford | 2009, 2011-Present | Baltimore Orioles | 2012 |
| Scott Rice | 2008 | New York Mets | 2013 |
| Rich Hill | 2015 | Boston Red Sox | 2015 |
| Tim Melville | 2017, 2019 | Minnesota Twins | 2017 |
| Quintin Berry | 2017 | Milwaukee Brewers | 2017 |
| Henderson Alvarez | 2017 | Philadelphia Phillies | 2017 |
| Wilkin Castillo | 2018 | Miami Marlins | 2019 |
| Fernando Abad | 2018 | San Francisco Giants | 2019 |
| Emilio Bonifacio | 2018 | Washington Nationals | 2020 |
| Mickey Jannis | 2015 | Baltimore Orioles | 2021 |
| Sean Nolin | 2019 | Washington Nationals | 2021 |
| Jose Cuas | 2018-19, 2021 | Kansas City Royals | 2022 |
| Deven Marrero | 2022 | New York Mets | 2022 |
| Rob Zastryzny | 2021 | New York Mets | 2022 |
| Zack Weiss | 2019 | Los Angeles Angels | 2022 |
| Michael Tonkin | 2019, 2021 | Atlanta Braves | 2023 |
| Matt Carasiti | 2022 | Colorado Rockies | 2023 |
| Brett Kennedy | 2022-23 | Cincinnati Reds | 2023 |
| Tyler Zuber | 2024 | Tampa Bay Rays | 2024 |
| Brady Feigl | 2022 | Pittsburgh Pirates | 2024 |
| Robert Stock | 2023 | Boston Red Sox | 2025 |